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doi: 10.1016/j.fitote.2019.104287, 103

10.1038/nature09779 424 WiddenH.PlaczekW

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The deficiency in one globin chain leads to an overall decrease in hemoglobin and the intracellular precipitation of the excess chain, which damages the membrane and leads to clinically evident hemolysis in the severe forms of alpha thalassemia (hemoglobin H disease) and beta thalassemia (intermedia and major)

(Clinical Principle) 5

These findings highlight the importance of optimal antioxidant supplementation in semen extenders to improve artificial insemination outcomes in Muscovy ducks