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& Seasholtz, A

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cytotoxicity data showed no toxicity to keratinocytes or fibroblasts across a six-log concentration range (0.0058 to 5800 micromolar) 3

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Loop E, K999 and R1000 are disordered in apo-NNT and R925 flips into an outward-facing orientation, opening the site to the solvent

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J Paediatr Child Health 2014;50:721e5

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The study showed both time-dependent and dose-dependent increases at mRNA and protein levels

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