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Reduced Expression of PDGF and PDGF Receptors During Impaired Wound Healing

IL-12 facilitates CD4+ T-cell differentiation into Th1 cells that secrete elevated levels of interferon-gamma (IFN-), which subsequently activates NK cells and cytotoxic T lymphocytes (CTLs), thereby enhancing their anti-tumoral functions (74)

When the body is dehydrated, it lacks the necessary fluids to carry out its normal functions, resulting in feelings of exhaustion and weakness

TMAO is formed in the liver from trimethylamine (TMA), a substance produced by gut bacteria from food-based compounds such as choline, carnitine, lecithin, betaine, gamma-butyrobetaine, and ergothioneine

Elife 26:e00348

Clinical alterations resulting from these mutations are hypothesized to be derived from either loss or gain of function of GCase and interaction with its substrates like glycosphingolipids (GSLs), glucosylceramide (GlcCer) and glucosylsphingosine (GlcSph)