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Because of this profound cellular mechanism, immense public interest has been generated regarding its systemic utility

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This study found that the majority of patients could not recognize the most common manifestations and/or comorbidities such as PsA, CVD, and axial symptoms/disease

[17] However, no large-scale, controlled trials have evaluated the efficacy or safety of ALA for pregnant patients, and thus there is insufficient evidence to consider it definitively safe

However, this protective effect is only observed a decade or more after a womans last pregnancy (311)(312)(313)