most common place for melanotic macule macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Melanotic Macules, Naevi, and Melanoma

Melanotic Macules, Naevi, and Melanoma Springer Nature Link Labial melanotic macule (brown spot on lip) (Stony Brook Case 1) dermatology dermatopathology Pigmented Lesions of the Oral Cavity Oral and Maxillofacial Surgery Clinics Oral pathology: Noting a pigmented macule that often presents a diagnostic dilemma Registered Dental Hygienists Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Oral pigmented lesions: Clinicopathologic features and review of the literature PMC

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