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1: Dakhore S, Nayer B, Hasegawa K

Redox imbalance is a condition in which there is an excess of free radicals in the body

In terms of efficacy, GH and IGF-1 both stimulated linear growth but some variables including the greater growth deficit in infants with Laron syndrome than those with isolated growth hormone deficiency, insufficient IGF-1 dose, or the IGF-1 dependency on the GH-linked stem cell population of prechondrocytes made GH more efficient in terms of linear growth stimulation (170, 171)

10.1038/tp.2016.22 [DOI] [PMC free article] [PubMed] [Google Scholar] Goldstein DS, Sullivan P, Holmes C, Miller GW, Alter S, Strong R, Mash DC, Kopin IJ, Sharabi Y, 2013