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Patients in all studies had moderate-to-severe OCD (DSM-III), with mean baseline ratings on the Yale-Brown Obsessive Compulsive Scale (YBOCS) ranging from 26 to 28 and a mean baseline rating of 10 on the NIMH Clinical Global Obsessive Compulsive Scale (NIMH-OC)

However, evidence shows that hepatic glutamine synthetase contributes to both enteral and systemic ammonia detoxification (Hussinger, 1983

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This wide range of expected lifespans, together with other aspects, has made dogs promising as model organisms for aging research (Gilmore and Greer, 2015