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Harwell, Atomic Energy Agency, Environment and Energy, 29 pp

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Iron homeostasis imbalance and ferroptosis in brain diseases

Although SARS-CoV-2 was originally hypothesized to induce neurological symptoms, such as loss of smell and taste and altered consciousness, through direct infection of the brain, multiple case reports demonstrate little to no virus within the CNS compartment, including among patients that died due to severe disease (Schurink et al., 2020

Additionally, H19, a significant lncRNA, regulates multiple signaling pathways in liver and colorectal cancer, affecting tumor cell proliferation and survival (11)

Parkinson-associated risk variant in distal enhancer of alpha-synuclein modulates target gene expression