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10.1016/j.abb.2008.06.004 Arch Biochem Biophys

Discussion Michael addition reaction has been widely applied in organic synthesis and bioconjugation to build carboncarbon and carbonheteroatom bonds based on its forward reaction

As discussed above, energy metabolism dysfunction is a characteristic sign of ALS disease and defects in skeletal muscle energy metabolism deeply contribute to disease progression (Dupuis et al., 2011)

Olde Rikkert MG, Verhey FR, Sijben JW, Bouwman FH, Dautzenberg PL, Lansink M et al

When consumed, molecular hydrogen (H) dissolves in bodily fluids and reacts directly with hydroxyl radicals (OH) to form water (HO) as its only byproduct