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On examination, she was afebrile, conscious, alert and oriented, noted to have pallor, bipedal oedema, hyperpigmentation over the tongue, bilateral hands and feet (Fig

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Carcinogenesis 32:138145

Early programmes, institutional studies, and preclinical model work examined how the compound class might influence receptor signalling, cellular adaptation, or tissue-level response patterns under controlled conditions

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Markedly elevated concentrations of total homocysteine (tHcy) in blood are the biochemical hallmark of cobalamin-related remethylation disorders