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When assessing TDP-43 solubility, we also observed a significant increase in RIPA insoluble phosphorylated TDP-43 at 1 hour recovery that was cleared by 3 hours post-stress recovery (Fig

However, in diabetes, disrupted autophagy may lead to aberrant cell death or senescence, hindering tissue repair (Wang et al., 2025a

Acknowledgements This work was supported by the Russian Science Foundation grants 19-74-30007 (A.A.M.) and 17-74-30030 (A.M., S.E., O.K.)

In Huntingtons disease (HD), oxidative stress plays a significant role in the neurodegenerative process

PGC-1 is a transcriptional coactivator that is closely related to energy metabolism and plays an important role in the process of mitochondrial synthesis and adaptive thermogenesis 59, 60