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in vitro studies on human brain tissues that had been oxidatively damaged by exposure to hydroxyl (OH) or superoxide (O 2 ) free radicals produced by Co 60 irradiation (Siddique et al., 2000)

These transcription factors play a critical role in regulating various cellular processes, including apoptosis (programmed cell death), oxidative stress response, and cell cycle regulation

Discover the Benefits Vitamin B12 is crucial in energy production, red blood cells, nerve function, and DNA synthesis

[DOI] [PubMed] [Google Scholar] Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, Shimizu-Yoshida Y, Koyabu M, Matsuyama M, Mori T, Kamihira T, Daikoku M, Migita K, Yatsuhashi H, Nozaki N, Shimoda S, Ishibashi H

Free Radic Biol Med 20(152):175185 Wilkinson JH, Baron DN, Moss DW, Walker PG (1972) Standardization of clinical enzyme assays: a reference method for aspartate and alanine transaminases

However, M2 ( N -glucuronide) and M4 (monooxy N -glucuronide) were also observed as circulating metabolites at 3.3% and 2.3% of dose respectively