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Constipation is the most frequent autonomic feature affecting PD individuals and is determined by both neurogenic and non-neurogenic factors, such as reduced mobility and abdominal muscle tone, a diet poor in fibers and insufficient fluid intake, all contributing to a prolonged gastrointestinal transit time and sometimes megacolon [251]

If it smells funny or smells like plastic, it's likely that chemicals have seeped in

Tanning : Prolonged sun exposure results in tanning, making certain body areas appear darker than your natural skin tone

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The heat required to evaporate liquid water into water vapor is the latent heat of vaporization which has a value of 540 cal/g (Figure 5.1.2)

This is not a direct drug effect but rather a consequence of significant caloric deficit and rapid body changes