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This can result in nerve damage and other adverse effects, as has been recently reported

Ishikawa T, Abe S, Watanabe T, et al

Because the pituitary remains largely unaffected and is able to maintain intracellular T3 levels while the rest of the body suffers from significantly reduced intracellular T3 levels, there is no elevation in thyroid-stimulating hormone (TSH) despite the presence of wide-spread tissue hypothyroidism, making the TSH and other standard blood tests a poor marker to determine the presence or absence of hypothyroidism

As typical for retrospective chart reviews, the outcome variables were limited to those that were systemically recorded on the patient charts during routine clinical outpatient visits, resulting in that some tests ( e.g

Four patients who were non-responsive to propranolol were treated with topiramate, and all of them had a satisfactory response

Valproic acid intoxication imitating brain death