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For example, altering the promoter regions of heat-responsive genes or deleting negative transcriptional repressors might increase the production of protective proteins like heat shock proteins (HSPs) or ROS-scavenging enzymes (Kan et al

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1 2 "Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry"

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(2024) suggested that a distance of 20 nm between the organelles ensures maximum efficiency of mitochondrial Ca 2+ uptake and restores mitochondrial Ca 2+ uptake during PD, whereas a shorter distance compromises efficient mitochondrial Ca 2+ uptake and oxidative metabolism, contributing to PD [71]

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