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Prediction of targets of curculigoside a in osteoporosis and rheumatoid arthritis using network pharmacology and experimental verification

50mg vial with 2.5ml bacteriostatic water: 50mg 2.5ml = 20mg/ml For 1mg dose: 1mg 20mg/ml = 0.05ml = 5 units on U-100 syringe 50mg vial with 2ml bacteriostatic water: 50mg 2ml = 25mg/ml For 1mg dose: 1mg 25mg/ml = 0.04ml = 4 units on U-100 syringe 100mg vial with 5ml bacteriostatic water: 100mg 5ml = 20mg/ml For 2mg dose: 2mg 20mg/ml = 0.1ml = 10 units on U-100 syringe Higher concentrations mean smaller injection volumes but require more precise syringe handling

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Although curcumin holds promise as an anti-cancer agent, its practical application is hindered by its limited water solubility and stability in vitro environments as well as its low bioavailability in vivo studies [270,271,272]