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35,36 Intracellular iron overload disrupts the iron regulatory protein/iron-responsive element (IRP/IRE) system, leading to upregulated translation of APP and consequent overproduction of A

Upon acute simulation in RAW 264.7 cells, we found that itaconate and succinate levels showed a similar trend, in which they initially accumulate and then decrease over the first 2432 h (Fig

A.de MartinoA.et al (2016)

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As evidence, the incidence rate in women greater than 40 years of ag shows a linear increase in BCC incidence rates [84]