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Fe 3+ in the intestinal cavity is reduced to Fe 2+ by duodenal cytochrome B, and then transported by divalent metal ion transporter 1 to the absorption cells of the intestinal mucosa epithelium

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Z-ligustilide restores Tamoxifen sensitivity of era negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of era

Int J Mol Sci (2013) 14(3):5380401

Tumor cells also outcompete T-cells for cystine by overexpressing SLC7A11, thereby reducing GSH levels and promoting ferroptotic cell death

Consistent with their findings, our results also demonstrated that the fruit extract contains multiple phytochemicals, including glycosides, alkaloids, phenols, flavonoids, saponins, tannins, proteins, amino acids, and carbohydrates