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In some embodiments, the compositions of the disclosure comprise at least about 12.6 mM of cannabinoid (e.g., a single cannabinoid such as CBD, or combination of cannabinoids)

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In all three buffers, 1 M ghrelin (Tocris) or ibutamoren (MK-0677, Tocris) was included

The starting conformations were obtained by manually binding GS(H) to a snapshot of the MD simulation of TRaQ-G and the crystal structure of Me-TRaQ-G, respectively