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Pediatr Nephrol 35(3):383397

Furthermore, recent studies have expanded its relevance by associating it with metabolic regulation, chronic pain, and the development of stress-related disorders such as depression, PTSD, obesity, and diabetes, consolidating FKBP51 as a potential therapeutic target (Hhle et al., 2019)

Revised on 11/24

BRCA2: Breast cancer gene 2

Anti-oxidation: removes hydroxyl free radicals and protects DNA from oxidative damage

This may imply conformational changes which don't allow the fragment to accept the helical regularity since disulfide bridges are stronger than the forces stabilizing alpha helix