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The disease is associated with several factors, including disruptions in purine metabolism (5), decreased UA excretion and excessive UA production (6,7)

Plant Mol Biol 87:473487 Google Scholar Duhoux, A, Pernin, F, Desserre, D Dlye, C (2017b) Herbicide safeners decrease sensitivity to herbicides inhibiting acetolactate-synthase and likely activate non-target-site-based resistance pathways in the major grass weed Lolium sp (rye-grass)

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230 In PD, brain-derived -syn accumulates in the livers of both mice and humans

Several cytoskeletal proteoforms were differentially enriched in frail brain, including an increase in abundance of multiple actin-binding Drebrin-1 (DBN1) peptides (Fig