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[10] demonstrated that a majority of participants with ASD receiving sulforaphane showed improvement in social interaction, abnormal behavior, and verbal communication

7 Outlook The precision management of DS faces critical challenges and opportunities, with future research prioritizing the following frontiers: Retinal-Brain Glial Dynamics as a Diagnostic Window: Building on the potential of non-invasive biomarkers like retinal imaging (e.g., OCT) highlighted for capturing glial activity, future studies should decipher the bidirectional signaling between retinal and brain glial cells (astrocytes, microglia