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Childhood trauma is associated with elevated anhedonia and altered core reward circuitry in major depression patients and controls

Some research suggests that a less efficient methylation cycle could influence several areas relevant to neurodevelopment

Jeney V, Balla G, Balla J

Biological analyses were performed on fasting blood samples, measuring folates, B12, zinc, cooper, magnesium, glutathione redox status, and folate receptor-alpha autoantibodies using immunoassays and biochemical assays

However, their low biocompatibility is limiting their biomedical applications due to the presence of toxic transition metal such as cadmium 12

Front Cell Neurosci 13(87):448587 Fredriksson I, Jayaram-Lindstrm N, Kalivas PW, Melas PA, Steensland P (2023) N-acetylcysteine improves impulse control and attenuates relapse-like alcohol intake in long-term drinking rats