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Citation: Maras B, Angiolella L, Mignogna G, Vavala E, Macone A, Colone M, et al

Combining B12 supplementation with medications that deplete it without monitoring

Improving Sleep Patterns Melatonin, the hormone that controls sleep-wake cycles, is produced in response to vitamin B12, affecting sleep patterns

30 minutes after breakfast and 30 minutes after dinner

Publication bias was judged by Begg's funnel plot and Egger's test ( trim and fill approach was applied in the case of an asymmetrical funnel plot to adjust for the potential publication bias ( Results Flow and Characteristics of Included Studies We identified 330 records through the literature search

acknowledges the funding provided by CONAHCYT in the form of scholarship as member of the National System of Researchers (SNI 1047863) and the financial support of Federico Baur Endowed Chair in Nanotechnology (ILST002-23ID69001)