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Interestingly, MT3 levels in the mutant SOD1 mouse model of ALS were reportedly elevated 76,77,78 , however, knocking out MT3 worsened phenotype and survival 79 , and retrograde viral delivery of MT3 was found to be beneficial 80

Furthermore, the translation of findings from in vitro and animal studies to human physiology presents another significant challenge

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Prognostic value of the albumin-bilirubin score in patients with non-Hodgkin lymphoma-associated hemophagocytic lymphohistiocytosis