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Chondrogenic maturation To mimic the in vivo differentiation of growth plate chondrocytes in vitro, confluent monolayers were switched to chondrogenic differentiation medium (growth medium supplemented with 50 g ml 1 l-ascorbic acid (Sigma-Aldrich), 10 ng ml 1 recombinant human transforming growth factor-1 (rhTGF-1

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