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Smaller, more metabolically active fat cells, higher energy, and improved body composition

Two people can take the same dose of tirzepatide and have vastly different outcomes based on genetics, starting body composition, activity level, diet quality, sleep patterns, stress levels, and dozens of other variables

This is due to the liver taking up all the circulating FFAs, which then interfere with insulin and IGF-1 signalling (as described above) and eventually leading to hepatic steatosis

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It is a small synthetic molecule that blocks an enzyme called NNMT (nicotinamide N-methyltransferase)