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doi:10.1093/eurheartj/ehaf174 Ebrahimi F, Ebrahimi R, Beer M, et al

There is so far no evidence that the subclade K strain produces more severe disease, according to the CDC

This can occur due to conditions such as pernicious anemia, gastrointestinal disorders like Crohns disease, or following gastrointestinal surgery

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The TM1 stalk (135-138) of CTR in the Cagri CT-like conformation also undergoes rearrangement relative to the bypass conformation, in which the phenyl of F137 1.28 packs against F15 Cagri , H18 Cagri and S19 Cagri (Fig