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Thus, repurposing existing drugs not only appears to be an attractive approach in search of innovative anti-biofilm drugs but also saves time and extensive effort of going through de novo drug optimization processes [167]

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Treatment: 1 RCT (n=240) suggests possible benefit for CIPN treatment (low certainty)

The decreased concentrations of BDNF (89), glial cell line-derived neurotrophic factor (GDNF), Artemin (ARTN) (90), nerve growth factor (NGF) (91), and vascular endothelial growth factor (VEGF) (92) are a good repetitive finding in depression