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For Stelara, see Exclusion Document for more information

[PubMed: 15578035] 103

Severe caloric restriction sometimes impairs concentration and mental clarity, likely due to low glucose availability and potential micronutrient deficiencies

That triple mechanism produced the most dramatic weight reduction data in modern clinical trials, with participants losing up to 24.2% of their body weight over 48 weeks

In support, the therapys beneficial effect in the rats with occluded bile ducts was relatively marked, as before in the occlusion-like syndrome and Budd-Chiarisyndrome studies [13,23,24,25]