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Sorafenib and erastin can activate the NFE2L2 pathway, resulting in the expression of antioxidant genes such as quinone oxidoreductase 1 (NQO1) and metallothionein 1G (MT1G) in HCC cells (87, 89)

Symptoms of this disorder often start during infancy and can include drowsiness, seizures that may be accompanied by involuntary jerking muscle movements of the arms, legs or head (myoclonic seizures), and intellectual disability

are "compounded" rather than FDA-approved mass-market drugs

Resources and support Lung Foundation Australia has information and support for people with lung conditions and their carers

Published 2020 Mar 2

doi:10.1002/jcc.20084