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Thus, we aimed at hypothesizing and providing some possible mechanisms linking oxidative stress to autoimmunity aspects and its implications for HT, as well as adjuvant therapeutic proposals to mitigate the deleterious effects

The analysis also highlighted downregulation in antioxidant and stress response pathways, such as reduced glutathione, along with changes in phenylalanine metabolism (e.g., 2,3-dihydro-2,3-dihydroxybenzoate), signaling pathways (e.g., tyrosine and arginine), carbohydrate metabolism (e.g., fructose 1-phosphate and allose), and nucleotide and nucleic acid metabolism (e.g., adenine and UDP)

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Moreover, curcumin has demonstrated efficacy in the treatment of acute lung injury and fatal acute respiratory distress syndrome caused by human coronaviruses in multiple trials (306)

Jang YS, Kang JH, Woo JK, Kim HM, Hwang JI, Lee SJ, et al