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Dosing & Reconstitution Guide Educational guide for reconstitution and weekly dosing Standard / Gradual Approach (1 mL = ~5.0 mg/mL) Frequency: Inject once weekly subcutaneously [1] [2]

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320,321 Additionally, NOX2-generated ROS are necessary for LC3 recruitment to phagosomes, revealing an autophagy-dependent antibacterial activity of NOX2 in phagocytes