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Systemic copper toxicity has not been a prominent signal in topical clinical studies

The observation of hemithioacetal 2 was relatively prolonged under acidic conditions (DCl, 2 equivalents), possibly relating to increased N -amino group protonation

Astrocyte-specific loss of CLEC16A exacerbates neuroinflammation and demyelination in an MS mouse model and corresponds with mitophagic deficits in human MS plaques, highlighting CLEC16A as a novel therapeutic target [245]

The most prevalent complaint of PD patients in nighttime sleep is many nightly awakes or fragmented sleep (Happe et al., 2001)

Such RNA-based networks have been implicated in ferroptosis regulation across diverse diseases including cancer, cardiovascular disease, and brain injury ( Pharmacologically, GPX4 remains a compelling yet challenging target

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Bibb MJ