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All of the above studies suggest that MT has the potential to improve many of the dysfunctions of NPD by improving the levels of endogenous opioid peptides in the PFC, hippocampus, and amygdala, or by blocking binding to opioid-like receptors, which affects the function of the PFC Hip-Amy circuit

The subjective motor experiences of daily living in apathetic patients were impaired, implying that these patients exhibit a more severe neurodegenerative pattern progression (den Brok et al., 2015

We developed a workflow with isotope-labelled internal standards and a calibration range as low as 0.0025 nM, ensuring detection of ultra-trace metabolites

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