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In: Katazung's Basic and Clinical Pharmacology

Some patients may use both forms depending on their goals, but this should only be done with provider supervision

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Methods 532, 113727

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p66shc negatively regulates insulin-like growth factor I signal transduction via inhibition of p52shc binding to Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 leading to impaired growth factor receptor-bound protein-2 membrane Mol