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Erlendson MJ, DArcy N, et al

Exp Neurol 392:115328

The peptide showed neuroprotective effects comparable to established treatments but with superior safety profiles

Abnormal intestinal permeability in subgroups of diarrhea-predominant irritable bowel syndromes

However, GW1929 significantly increased PPAR expression in these three subsets ( Figure 6B ), possibly because its potency is approximately equivalent to that of rosiglitazone and much higher than that of MEHP ( Figure 6C )