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Moreover, the authors extended this mechanism to senescent cancer cells and demonstrated that these cells are more efficient than immunogenic cell death to induce immune system protection against tumor relapse

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Thus, MASLD patients contrast to patients that have progressed to liver cirrhosis, as these patients are more susceptible to developing sarcopenia, a chronic catabolic state with increased energy expenditure, decreased appetite, low protein synthesis, and the development of ascites or portosystemic shunts that contribute to muscle atrophy (130)