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In addition, the pleiotropic metabolic effects of SGLT2 inhibitors make it difficult to attribute the observed changes solely to immune or signaling modulation rather than secondary metabolic improvement

Li Y, Mei H, Liu Y, Li Z, Qamar H, Yu M, et al

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Its ability to cross the blood-brain barrier allows it to have a more direct influence on brain health

In contrast to our observations in OC, high expression of CRAT in melanoma correlates with reduced progression-free and overall survival [21]

1), which is consistent with previously reported decreases in acetylcarnitine in other fatigue-associated conditions and supports our hypothesis that acetylcarnitine supplementation may be beneficial in the treatment of long COVID-associated neuropsychiatric symptoms