Additional caution or monitoring may be appropriate in research settings involving: Active cancer- or tumor-related research models, where antioxidant-related pathways may influence cellular-response or treatment-response mechanisms Severe asthma or hypersensitivity-prone research models, as rare sensitivity-related observations have been reported in some experimental contexts Sulfur-sensitive research models, due to Glutathione containing a thiol (sulfur-containing) group Complex hepatic-function or detoxification-related investigations, where antioxidant modulation may influence oxidative-stress or liver-related biomarkers Research conditions, research amounts, protocol duration, administration frequency, and concurrent compounds may influence tolerability observations across experimental settings
This work was supported by a grant of the Ministry of Research, Innovation and Digitization, under the Romanias National Recovery and Resilience Plan funded by EU Next Generation EU program, project Artificial intelligence-powered personalized health and genomics libraries for the analysis of long-term effects in COVID-19 patients (AI-PHGL-COVID) number 760073/23.05.2023, code 285/30.11.2022, within Pillar III, Component C9, Investment 8 and by a grant of the Ministry of Research, Innovation and Digitization, CNCS, UEFISCDI, project number PN-III-Pl-1.1-PD-2021-0273, within PNCDI III
[35] investigated and characterized 4 Fe-SODs in epimastigotes, mainly cytosolic
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