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Persistent or worsening symptoms beyond the initial treatment period should prompt medical review

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While AGE exposure alone showed a modest, non-significant trend toward increased secretion of Th2 (IL-4, IL-5) and pro-inflammatory cytokines (TNF), exposure to FM-HAGE significantly enhanced the production of these cytokines (Supplementary Fig

Rational design and synthesis of 4-o-substituted phenylmethylenethiosemicarbazones as novel tyrosinase inhibitors