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Controls, calibration and reporting standards Implement specificity controls (SOD, catalase/GPx mimetics, peroxiredoxin modulation, iron chelators), genetic tools (isoform knockdown/knockout, rescue) and pharmacologic orthogonality (distinct inhibitor classes)

However, it could not address symptomatic improvement of DPN in clinical trials, but it only improved nerve conduction velocity [79,80]

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After incubation with constant shaking at 37C in the dark for 1 h, glucose (100 L, 4 mg/mL) and MB (100 L, 100 g/mL) were added into the system and then incubated at 37C for 5 h

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