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When absorbed directly through the gut, as food or tablets, your body will only take on as much B12 as it needs, and the excess will pass through your urine

Wellness 20 July 2025 7 min read Needle Size for a B12 Injection: A Simple Guide By Alaiyka Parvez Owner, CoLaz Aesthetics Clinic The short version For an intramuscular B12 injection, the usual choice is a 22 to 25 gauge needle, 1 to 1.5 inches long, given at 90 degrees into the deltoid

Like B12 shots, the nasal spray gets vitamin B12 directly into your bloodstream (via the nostrils), bypassing your digestive system

When those systems are sluggish, even a solid diet and exercise routine can feel like it's not working

[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Imai S

Another study conducted by the University of California found that B12 supplements improved energy levels and reduced fatigue in individuals with chronic fatigue syndrome