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For years, researchers suspected it existed naturally in the human body, and in 2017, Epitalon was detected for the first time in physiological pineal gland extract, confirming it as an endogenous compound

This collagen boosting ability extends beyond skin health and may also support joint, tendon, and ligament health, which is essential for maintaining mobility and function in old age

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The role of the Rho/ROCK pathway in intestinal fibrosis is to control the expression of connective tissue growth factor (CTGF), which mediates myofibroblast differentiation, fibroblast proliferation and collagen synthesis (Gervaz et al., 2009)

In animal-based models of depressive-like behavior, administration of the peptide was linked to attenuation of behavioral symptoms, indicating possible antidepressant-like activity under experimental conditions (25,26)