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Chronic oxidative stress in synovial T-lymphocytes of patients with RA results from intracellular ROS production (mainly H 2 O 2 ) (194), and ROS may be involved in destructive pathological events of RA

A study has demonstrated that neomycin is as effective as lactulose in 33 patients [62], although, in another randomized study by Strauss, neomycin was shown to be no better than a placebo in patients with HE [63]

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2003 and Khan 2011)

Mitochondria: A connecting link in the major depressive disorder jigsaw

PHYSIOLOGICAL OVERVIEW OF MELATONIN Melatonin is a prevalent biological molecule, produced and secreted by the pineal gland in response to darkness, that acts as a regulator that aligns the physiology of the organism according to the day/night and seasonal changes of the external environment[32]