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SLC1A5 promotes intracellular glutamine accumulation, which in turn increases leucine uptake via the SLC7A5 (LAT1) transporter, a process that is critical for activation of the mTORC1 signaling pathway via the Ragulator-Rag complex

Thus, Nrf2 activates both the oxidative and nonoxidative PPP to increase NADPH and nucleotide production 51

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Specific association of a CLEC16A/KIAA0350 polymorphism with NOD2/CARD15 - Crohns disease patients