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Adults Over 35 With Central Obesity This demographic faces two compounding issues: declining growth hormone production and increasing visceral fat accumulation

All of these changes can make it harder to conceive naturally and increase the risk of health issues in children

10.1186/1472-6882-13-9 42 ZhangB.ChenY.ShenQ.LiuG.YeJ.SunG.et al (2016)

Individuals with severe gastroparesis delayed gastric emptying could worsen symptoms in this group, and retatrutide is likely to be unsuitable