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A report demonstrating a reduction in blood pressure in humans by ingestion of dietary levels of inorganic nitrate

The E167K variant enhances the interaction between TM6SF2 and the PNPLA3 variant I148M, which inhibits the function of PNPLA3 in mediating the transfer of polyunsaturated fatty acids (PUFAs) from TG to phosphatidylcholine, leading to increased accumulation of polyunsaturated TG in the liver and exacerbation of liver injury [271]