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Tier 3 patients often experience significant improvements in energy levels and brain fog within 2-4 weeks, with substantial weight loss and metabolic improvements within 8-12 weeks, and continued progress over 6-12 months

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Zick and colleagues [117] have elegantly summarised recent evidence that show how IRS also possess serine residues that can be phosphorylated

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Allowing the powder to reach room temperature before adding water prevents thermal shock that denatures the peptide structure