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Description

Because of similar pharmacological properties, it is reasonable to expect similar risk with the concomitant use of other CNS depressant drugs with opioid analgesics (see PRECAUTIONS, Drug Interactions)

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investigated Hachimijiogan (HJG), revealing its ability to induce neurite outgrowth in PC12 cells by acting as a nerve growth factor (NGF)

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Subjective improvement without objective measurement is unreliable

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PE-22-28 SCIENTIFIC DATA SUMMARY Parameter Molecular Weight Amino Acid Length Half-Life Bioavailability Detection Window Value Application TREK-1 Inhibition Antidepressant Effects Cognitive Enhancement Neuroprotection Studies Dose Range Outcome Study Type Optimization Study TREK-1 Mechanism Behavioral Studies Population Results Limitations Parameter Acute Toxicity Organ Toxicity Adverse Events Long-term Safety Finding Authority FDA WADA DEA Classification Status Peptides work best as one part of a complete, medically supervised plan

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Food and Drug Administration (FDA) (2016)

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